
Effects > Distort > Jitter
You absolutely must be using the latest version of Paint.NET (3.10) to use this plugin.
This plugin "Jitters" each row of pixels by a random amount. The angle, width of the rows, intensity of the effect, spacing between jittered rows, and edge-behavior are all adjustable.
You can also toggle antialiasing.

Something interesting you can do with this (very rough; I made it in 5 minutes based on a very old sig of mine):



























