This reminds me so much of Fullmetal Alchemist...
Let me try real quick.
Awesome!!!(For the top zoom, I used Motion blur. I currently don't have that plugin)
Two ways you could go.. One, LOTS of make-up(Because you know they're all 'dolled' up from makeup) or two you could do this tutorial right here. (It's for photoshop but I've used it on Paint.Net with success)
That one's my favorite. It looks really cool.
Anyway, I did some fan art for a friend of mine (or I just took her photo and made it all pimped out!) http://pure-nonsense.deviantart.com/art/quot-Come-with-me-quot-67889143
I really like this one, I don't remember what I did, so I can't make it again. T-T
I tried to do it, but it looked REALLY crappy. Like a a cheesy Horror movie.