I had read some where that its possible to do 'mipmapping' with paint.net. I've used paint.net for a long time now and haven't ever seen this. Nor have I actually looking for it since I read that. I'm trying to make textures for a game, and the only way I have found is through PS which has a 'make mipmap' tool. If there isn't a way to do this, You should add it to the next version