How to reproduce:
1. Right-Click on any picture in Opera Webbrowser and select "Copy to clipboard"
2. Paste into Paint.NET
Result:
Picture is shifted 6 pixels to the right.
Pasting is fine in "normal" Paint
Version:
Paint.NET Beta 1 3.0.2525.34975
This seems to be related to this issue: http://paintdotnet.12.forumer.com/viewtopic.php?t=2354 "Paste from PrintScreen in Remote Desktop"