I've been using paint.net for some time, I prefer it much more than Photoshop IMO. I notice it lacks the ability to work with 3d Files. I work with UV sheets and trying to get them to wrap all the time. I would prefer to be able to see the Small details I add while I am in paint.net reflect directly on the obj/3d object during real time. Also, i am not too sure if this is implemented in the program, but having a channel Tab kinda like how Photoshop has their set.