I'm having a similar problem but I can't re-install. It won't let me. It keeps giving me the message:
System.DllNotFoundException: Unable to load DLL 'Native.x86\PaintDotNet.Native.x86.dll': The referenced assembly is not installed on your system. (Exception from HRESULT: 0x800736B3)
at PaintDotNet.SystemLayer.PdnNativeMethods.x86.CpuID(UInt32* prgnCpuInfo, Int32 nCpuInfoLen, UInt32 nInfoType)
at PaintDotNet.SystemLayer.PdnNativeMethods.CpuID(UInt32* prgnCpuInfo, Int32 nCpuInfoLen, UInt32 nInfoType) in D:\src\pdn\paintdotnet\src\SystemLayer\PdnNativeMethods.cs:line 88
at PaintDotNet.SystemLayer.Processor.GetProcessorFeatures() in D:\src\pdn\paintdotnet\src\SystemLayer\Processor.cs:line 355
at PaintDotNet.SystemLayer.Processor.IsFeaturePresent(ProcessorFeature feature) in D:\src\pdn\paintdotnet\src\SystemLayer\Processor.cs:line 416
at PaintDotNet.Setup.InstallingPage.d__1f.MoveNext() in D:\src\pdn\paintdotnet\src\SetupFrontEnd\InstallingPage.cs:line 890
at PaintDotNet.Threading.IterativeTask.IterativeTaskAnon.d__0.MoveNext() in D:\src\pdn\paintdotnet\src\Core\Threading\IterativeTask.cs:line 36
at PaintDotNet.Threading.IterativeTask`1.<>c__DisplayClass1.b__0() in D:\src\pdn\paintdotnet\src\Core\Threading\IterativeTask`1.cs:line 77