Initially, I also thought it is the problem of my hard disk. But that is not the case. Hard disk check is done. Health is good. The problem only happens with Paint.Net and it is reproducible. For example, after saving the file, if you close the file and then close Paint.Net, nothing will happen. Things will be fine. However, when the file is open in the Paint.Net and you close the program it will lead to the hard disk error message. So I think it has something to do with Paint.Net. However, Paint.Net does not crash, so I can not submit any crash report.