[Saving a File - ACCESS DENIED]

How do I check this Controlled Folder access is blocked by Windows 10 Defender?

[Saving a File - ACCESS DENIED]

This happens to each file graphic file, whether .jpg or .png.

My firewall is avast. I had it before this started with the graphics file. I am using the latest version of paintnet
I am trying to save it to my hard drive, not uploading to onedrive or dropbox.

Thanks for your efforts!

Frank

[Saving a File - ACCESS DENIED]

I'm sorry, I don't know. 
It used to not do this. I don't know if I inadvertently changed a setting.
It is not read-only 

I am not saving it to Dropbox, etc.

 

[Saving a File - ACCESS DENIED]

How do I stop getting the message "Access Denied" when I try to save a file after I have cropped it but have not changed its name. I get an error message that I must change the name to save it. (see attached error message).  This only started recently. I uninstalled the program and reinstalled but I get the same message. 
THANKS FOR YOUR HELP!!