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paint.net won't start

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Having used paint.net happily for quite some time (great program by the way!) it will no longer start since I installed office 2010 and produces the following error:

Paint.net has encountered a problem and needs to close. We are sorry for the inconvenience.

I suspect the problem may be related to the Microsoft .Net Framework 4 Client profile but I don't have anything concrete to go on. And I've tried repairing .Net Framework 3.5 SP 1, as well as un and reinstalling it. I've also un and reinstalled paint.net too but the error is always the same...


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There isn't one on the desktop or elsewhere on the drive... What should I do?

Symantec Endpoint Protection 11 was the culprit. Upgrading the client to the latest official symantec patch release (RU6) was the trigger...

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