Images that aren't created from scratch, when saved as PNG\GIF to be placed online, may have pixels with, for instance, several shades of black (ie. several dark greys), all more or less looking the same but different, never the less. Being able to convert those to a single color would improve the end result. Likewise, often (always?) a scanned image comes with pixels with -- I'm not sure what to call them (English is not my mother language) -- off or odd colors. What I meant with "fine tuning" is just this: being capable of eliminating those artifacts, with complete control in preview mode, when saving the file.
In Photoshop, using "Save for web" and then choosing PNG allows that.