A nice mention of Paint.NET in this two minute video interview posted today on Web Worker Daily:
http://webworkerdaily.com/2009/03/24/whats-your-favorite-web-app-wagner-james-au/
I'm not sure about the web app part but thought it was definitely worth sharing nonetheless. The post links to Paint.NET and the video is up on Vimeo as well.
Btw, I'm Michele. I have been perusing the forums and enjoying the plugins and tutorials for a little while now, but this is my first post. It is very nice to meet you!