Hello AndrewDavid, thanks for your suggestions.
My fonts are installed in C:\WINDOWS\Fonts and in the Settings I have not found a Font menu but in the Tools menu, in the Text section (see image) there is a font combobox that behave in the same manner as the one in the main Paint.NET interface: if I open it, Paint takes 100% CPU.
In other application (Word) I can use fonts without problems.
I have downloaded and installed a font and I can see it both in Paint than in Word (but Paint takes 100% CPU...)
I hope that the problem is not not updating Windows.
I have this problem only witn this last version of Paint, now I look for the previous one.