Yes’, I do use custom screen scaling, that’s worked flawlessly with Paint.Net.
Tested & RESET the Scale and layout “100% (Recommended)” to no avail.
Several Win10x64 reboots with varied settings.
Clean reinstalled the previous & currant Nvidia GPU driver.
Reinstalled (AForge.dll, AForge.Imaging.dll, QuadrilateralCorrection.dll)
Ran a backup of “paint.net.4.3.2.x64.exe”, with custom monitor Scaling.
The plugin working in its entirety on 4.3.2. & up to 4.3.3 alpha build 7988.
Reran Paint.Net 4.3.3, today Unable to get the plugin interface working.