For the UWP version, I'm having a similar problem as this topic: https://forums.getpaint.net/topic/113700-set-paintnet-from-windows-app-store-as-default-editor-in-context-menu/
The issue is that when editing the registry, I can't figure out how to get the paintdotnet: protocol to work.
Note that this is specifically for being able to right-click on an image file and choose the "Edit" item. Right-clicking and selecting "open with" works correctly, etc.
If I use any combination of quotation marks and spaces for paintdotnet:%1, then there's an access error complaining about permissions.
This could very well be due to Windows not understanding the protocol (I get the same error if I misspell paintdotnet), but it could be because I'm typing something else wrong.
If I use start paintdotnet:%1, it actually does the same thing as if I just use start, which is to open the "what do you want to open this file with?" dialog.