I don't know if this makes any difference or not, but I also have another GMIC installed on my system as the GIMP plugin. The thing that I thought was odd is this: when I first launched the GMIC plugin in paint.NET, the plugin's filter list showed all 519 filters plus all of my Favorites which I had set in the GIMP's plugin. This makes me believe that the paint.NET plugin is somehow referencing GIMP's gmic folder which is located at C:\Users\DB KETTREY\AppData\Roaming\gmic.
As a test, I moved GIMP's gmic folder completely out of the AppData folder, then relaunched the gmic plugin in paint.NET. Lo and behold, the gmic plugin then showed just the basic 300+ filters and NO Favorites, which is what I would have expected it to do. But paint.NET still crashed, regardless.
This makes me think that the paint.NET plugin and the GIMP plugin (and their dll's, perhaps) somehow intermingle in a bad way.