I'm having the same issue. PDN crashes every time I open it. However, though my Shapes folder is empty, renaming it (to Shapes_bak) allows me to open PDN.
...Well, it opened once and stayed open. But after that it now is back to crashing on every open.
System.AccessViolationException: Attempted to read or write protected memory. This is often an indication that other memory is corrupt. (PaintDotNet.Controls.LayersStrip)
at PaintDotNet.SystemLayer.Native.x64.Direct2D.D2DRenderTarget.EndDraw(Tag& tag1, Tag& tag2)
at PaintDotNet.Direct2D.RenderTargetExtensions.EndDraw(IRenderTarget renderTarget) in d:\src\pdn\paintdotnet\src\Core\Direct2D\RenderTargetExtensions.cs:line 18
at PaintDotNet.Controls.Direct2DControlHandler.RelayGdiPaintImpl(GdiPaintContext ctx) in d:\src\pdn\paintdotnet\src\Framework\Controls\Direct2DControlHandler.cs:line 683
at PaintDotNet.Controls.Direct2DControlHandler.RelayGdiPaint(GdiPaintContext ctx) in d:\src\pdn\paintdotnet\src\Framework\Controls\Direct2DControlHandler.cs:line 494
at PaintDotNet.Controls.Direct2DControl.OnGdiPaint(GdiPaintContext ctx) in d:\src\pdn\paintdotnet\src\Framework\Controls\Direct2DControl.cs:line 342
at PaintDotNet.SystemLayer.GdiPaintHandler.OnWmPaint(Message& m) in d:\src\pdn\paintdotnet\src\SystemLayer\GdiPaintHandler.cs:line 184
at PaintDotNet.SystemLayer.GdiPaintHandler.RelayWndProc(Message& m) in d:\src\pdn\paintdotnet\src\SystemLayer\GdiPaintHandler.cs:line 233
at PaintDotNet.SystemLayer.GdiPaintControl.WndProc(Message& m) in d:\src\pdn\paintdotnet\src\SystemLayer\GdiPaintControl.cs:line 130
at System.Windows.Forms.NativeWindow.Callback(IntPtr hWnd, Int32 msg, IntPtr wparam, IntPtr lparam)
